Autophagy in cancer

doi:10.12703/p7-18

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Autophagy in cancer

3 Feb 2015

Abstract excerpt

Autophagy is a catabolic degradation process in which cellular proteins and organelles are engulfed by double-membrane autophagosomes and degraded in lysosomes. Autophagy has emerged as a critical pathway in tumor development and cancer therapy, although its precise function remains a conundrum. The current consensus is that autophagy has a dual role in cancer. On the one hand, autophagy functions as a tumor...

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PMID: 25750736
DOI: 10.12703/p7-18

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