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Autophagy in Cancer Therapy

15 Jun 2017

Abstract excerpt

lysosomes. It serves to mitigate cellular stress and to provide metabolic precursors especially upon starvation. Thereby, autophagy can support the survival of cancer cells. In addition, there is now convincing evidence showing that under certain conditions autophagy can also foster cell death. This dual function of autophagy is also relevant upon anticancer treatment, as many chemotherapeutic agents engage...

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PMID: 28674677
DOI: 10.3389/fonc.2017.00128

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