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Article

Cerebrospinal fluid tau levels are a marker for molecular subtype in sporadic Creutzfeldt-Jakob disease.

Neurobiology of aging - 1 May 2015

Karch André, Hermann Peter, Ponto Claudia, Schmitz Matthias, Arora Amandeep, Zafar Saima, Llorens Franc, Müller-Heine Annika, Zerr Inga

Abstract excerpt

The molecular subtype of sporadic Creutzfeldt-Jakob disease (sCJD) is an important prognostic marker for patient survival. However, subtype determination is not possible during lifetime. Because the rate of disease progression is associated with the molecular subtype, this study aimed at investigating if total tau, a marker of neuronal death, allows premortem diagnosis of molecular subtype when codon 129 genotype...

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PMID: 25749129
DOI: 10.1016/j.neurobiolaging.2015.01.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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