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Article

Gene functionality's influence on the second codon: A large-scale survey of second codon composition in three domains.

Genomics - 1 Aug 2010

Tang Sen-Lin, Chang Bill C H, Halgamuge Saman K

Abstract excerpt

The second codon of a transcript, besides encoding for an amino acid, is now known to also have multiple molecular functions and is involved in translation efficiency and protein turn-over and maturation processing. These multiple purposes therefore make the selection constraints on this codon's composition more complex. To examine the biological significance of various permutations of the second codon, we...

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PMID: 20417269
DOI: 10.1016/j.ygeno.2010.04.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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