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Article

Activation of the GP130-STAT3 axis and its potential implications in nonalcoholic fatty liver disease.

American journal of physiology. Gastrointestinal and liver physiology - 1 May 2015

Min Hae-Ki, Mirshahi Faridoddin, Verdianelli Aurora, Pacana Tommy, Patel Vaishali, Park Chun-Geon, Choi Aejin, Lee Jeong-Hoon, Park Chung-Berm, Ren Shunlin, Sanyal Arun J

Abstract excerpt

The status of the GP130-STAT3 signaling pathway in humans with nonalcoholic fatty liver disease (NAFLD) and its relevance to disease pathogenesis are unknown. The expression of the gp130-STAT3 axis and gp130 cytokine receptors were studied in subjects with varying phenotypes of NAFLD including nonalcoholic steatohepatitis (NASH) and compared with lean and weight-matched controls without NAFLD. Gp130 and its...

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Share to Cytokine Receptor gp130
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25747354
DOI: 10.1152/ajpgi.00390.2014
PMCID: PMC4421014

Genes

STAT3
ATG7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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