Article

Palmitate and Western diet induce oxidative damage and impairment of mitophagy in hepatocytes - reversal by a neurotrophic factor

2022-07-07

Abstract excerpt

Nonalcoholic fatty liver disease (NAFLD) is associated with increased oxidative stress that leads to hepatocyte and mitochondrial damage. In this study we investigated the mechanisms involved in the induction of oxidative stress and impairment of mitochondrial quality control and mitophagy in hepatocytes by the saturated fatty acid palmitate and Western diet feeding in mice and if their harmful effects could be re...

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Literature Corpus work: bf5d6fb0-235b-533c-89f0-b5fd0552dd59
DOI: 10.21203/rs.3.rs-1677830/v1

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