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Article

TLR7- and TLR9-responsive human B cells share phenotypic and genetic characteristics.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2015

Simchoni Noa, Cunningham-Rundles Charlotte

Abstract excerpt

B cells activated by nucleic acid-sensing TLR7 and TLR9 proliferate and secrete immune globulins. Memory B cells are presumably more responsive due to higher TLR expression levels, but selectivity and differential outcomes remain largely unknown. In this study, peripheral blood human B cells were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25740945
DOI: 10.4049/jimmunol.1402690
PMCID: PMC4369401

Genes

TLR7
TLR9
BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25740945-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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