Article
Association of IL-1R2 genetic polymorphisms with the susceptibility of ankylosing spondylitis in Northern Chinese Han population.
Modern rheumatology - 1 Jan 2015
Xia Yu, Liu Yi-Qing, Chen Kun, Wang Lai-Cheng, Ma Chun-Yan, Zhao Yue-Ran
Abstract excerpt
OBJECTIVES: Previous Genome-wide association studies (GWAS) have demonstrated Interleukin-1 receptor 2 (IL-1R2) was strongly associated with susceptibility to ankylosing spondylitis (AS). The aim of this study was to replicate the association of IL-1R2 single-nucleotide polymorphisms (SNPs) with AS in the northern Han Chinese. METHODS: A total of 490 AS patients and 580 matched healthy controls were enrolled in...
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