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Article

Determinants of intestinal permeability in healthy first-degree relatives of individuals with Crohn's disease.

Inflammatory bowel diseases - 1 Apr 2015

Kevans David, Turpin Williams, Madsen Karen, Meddings Jon, Shestopaloff Konstantin, Xu Wei, Moreno-Hagelsieb Gabriel, Griffiths Anne, Silverberg Mark S, Paterson Andrew, Croitoru Kenneth

Abstract excerpt

BACKGROUND: The Genetics, Environmental, Microbial Project is a multicenter study assessing etiological factors in Crohn's disease by studying healthy first-degree relatives (FDRs) of individuals affected by Crohn's disease. We aimed to evaluate the contribution of genetic, microbial, and environmental factors to the determination of intestinal permeability in healthy FDRs. METHODS: IP was assessed using the...

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Identifiers

PMID: 25734694
DOI: 10.1097/MIB.0000000000000323

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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