Article
Cardiomyocytes have mosaic patterns of protein expression.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology - 1 Jan 2000
Wang Tony Y, Lee Dongwon, Fox-Talbot Karen, Arking Dan E, Chakravarti Aravinda, Halushka Marc K
Abstract excerpt
Skeletal myocytes have well-established fast and slow twitch fibers with unique gene and protein specific expression patterns. By immunohistochemical staining, these show a mosaic pattern across myocytes. We hypothesized cardiac myocytes may behave similarly where some proteins are differentially expressed between mature cardiomyocytes. We utilized the tool HPASubC on over 52,000 cardiac images of the Human...
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