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Article

Prevalence of incompletely penetrant Huntington's disease alleles among individuals with major depressive disorder.

The American journal of psychiatry - 1 May 2010

Perlis Roy H, Smoller Jordan W, Mysore Jayalakshmi, Sun Mei, Gillis Tammy, Purcell Shaun, Rietschel Marcella, Nöthen Markus M, Witt Stephanie, Maier Wolfgang, Iosifescu Dan V, Sullivan Patrick, Rush A John, Fava Maurizio, Breiter Hans, Macdonald Marcy, Gusella James

Abstract excerpt

OBJECTIVE: Presymptomatic individuals with the Huntingtin (HTT) CAG expansion mutation that causes Huntington's disease may have higher levels of depressive symptoms than healthy comparison populations. However, the prevalence of HTT CAG repeat expansions among individuals diagnosed with major de...

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Identifiers

PMID: 20360314
DOI: 10.1176/appi.ajp.2009.09070973
PMCID: PMC3114558

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20360314-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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