Article
The Huntington's Disease Gene in an Italian Cohort of Patients with Bipolar Disorder.
Genes - 25 Aug 2023
Ferrari Camilla, Capacci Elena, Bagnoli Silvia, Ingannato Assunta, Sorbi Sandro, Nacmias Benedetta
Abstract excerpt
BACKGROUND AND OBJECTIVES: Huntington's disease (HD) is characterized by motor, cognitive and psychiatric manifestations and caused by an expansion of CAG repeats over 35 triplets on the huntingtin (HTT) gene. However, expansions in the range 27-35 repeats (intermediate allele) can be associated with pathological phenotypes. The onset of HD is conventionally defined by the onset of motor symptoms, but psychiatric...
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