Article
Study of the Huntington's disease (HD) gene CAG repeats in schizophrenic patients shows overlap of the normal and HD affected ranges but absence of correlation with schizophrenia.
Journal of medical genetics - 1 Sept 1994
Rubinsztein D C, Leggo J, Goodburn S, Crow T J, Lofthouse R, DeLisi L E, Barton D E, Ferguson-Smith M A
Abstract excerpt
The CAG repeats in the Huntington's disease gene were investigated in chromosomes from 71 unrelated schizophrenic persons and 18 patients with schizoaffective disorder in order to determine if any of these patients had abnormal expansions. All of the probands had repeat sizes in the normal range (< 35 repeats) and there was no significant difference between the allele distributions of these patients and the...
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