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Article

Human brain microvascular endothelial cells resist elongation due to shear stress.

Microvascular research - 1 May 2015

Reinitz Adam, DeStefano Jackson, Ye Mao, Wong Andrew D, Searson Peter C

Abstract excerpt

Endothelial cells in straight sections of vessels are known to elongate and align in the direction of flow. This phenotype has been replicated in confluent monolayers of bovine aortic endothelial cells and human umbilical vein endothelial cells (HUVECs) in cell culture under physiological shear stress. Here we report on the morphological response of human brain microvascular endothelial cells (HBMECs) in...

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Source

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Identifiers

PMID: 25725258
DOI: 10.1016/j.mvr.2015.02.008
PMCID: PMC4426013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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