Article
Sul1 and Sul2 sulfate transceptors signal to protein kinase A upon exit of sulfur starvation.
The Journal of biological chemistry - 17 Apr 2015
Kankipati Harish Nag, Rubio-Texeira Marta, Castermans Dries, Diallinas George, Thevelein Johan M
Abstract excerpt
Sulfate is an essential nutrient with pronounced regulatory effects on cellular metabolism and proliferation. Little is known, however, about how sulfate is sensed by cells. Sul1 and Sul2 are sulfate transporters in the yeast Saccharomyces cerevisiae, strongly induced upon sulfur starvation and endocytosed upon the addition of sulfate. We reveal Sul1,2-dependent activation of PKA targets upon sulfate-induced exit...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
