Article
Competitive intra- and extracellular nutrient sensing by the transporter homologue Ssy1p.
The Journal of cell biology - 8 May 2006
Wu Boqian, Ottow Kim, Poulsen Peter, Gaber Richard F, Albers Eva, Kielland-Brandt Morten C
Abstract excerpt
Recent studies of Saccharomyces cerevisiae revealed sensors that detect extracellular amino acids (Ssy1p) or glucose (Snf3p and Rgt2p) and are evolutionarily related to the transporters of these nutrients. An intriguing question is whether the evolutionary transformation of transporters into nontransporting sensors reflects a homeostatic capability of transporter-like sensors that could not be easily attained by...
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