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Ammonium permease-based sensing mechanism for rapid ammonium activation of the protein kinase A pathway in yeast.

Molecular microbiology - 1 Mar 2006

Van Nuland An, Vandormael Patrick, Donaton Monica, Alenquer Marta, Lourenço Artur, Quintino Edgar, Versele Matthias, Thevelein Johan M

Abstract excerpt

In the yeast Saccharomyces cerevisiae starvation for nitrogen on a glucose-containing medium causes entrance into G0 and downregulation of all targets of the PKA pathway. Re-addition of a nitrogen source in the presence of glucose causes rapid activation of trehalase and other PKA targets. Trehalase activation upon ammonium re-supplementation is dependent on PKA activity, but not on its regulatory subunit nor is...

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PMID: 16468990
DOI: 10.1111/j.1365-2958.2005.05043.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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