Article
Etv2 and fli1b function together as key regulators of vasculogenesis and angiogenesis.
Arteriosclerosis, thrombosis, and vascular biology - 1 Apr 2015
Craig Michael P, Grajevskaja Viktorija, Liao Hsin-Kai, Balciuniene Jorune, Ekker Stephen C, Park Joo-Seop, Essner Jeffrey J, Balciunas Darius, Sumanas Saulius
Abstract excerpt
OBJECTIVE: The E26 transformation-specific domain transcription factor Etv2/Etsrp/ER71 is a master regulator of vascular endothelial differentiation during vasculogenesis, although its later role in sprouting angiogenesis remains unknown. Here, we investigated in the zebrafish model a role for Etv2 and related E26 transformation-specific factors, Fli1a and Fli1b in developmental angiogenesis. APPROACH AND...
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