Article
CA-SSR1 Polymorphism in Intron 1 of the EGFR Gene in Patients with Malignant Tumors Who Develop Acneiform Rash Associated with the Use of Cetuximab.
Molecular diagnosis & therapy - 1 Apr 2015
Jarząbek Tomasz, Rucińska Monika, Rogowski Wojciech, Lewandowska Marzena, Tujakowski Jerzy, Habib Maja, Kowalczyk Anna, Byszek Agnieszka, Dziadziuszko Rafał, Nawrocki Sergiusz
Abstract excerpt
BACKGROUND AND OBJECTIVE: Epidermal growth factor receptor (EGFR) inhibitors are not equally effective in all cancer patients. One potential clinical factor that could help in selecting patients who may benefit from treatment with cetuximab is acneiform rash, which correlates with the clinical response to EGFR inhibitors. Some previous studies have suggested that the tendency to develop rash may depend on...
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