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Article

HLA polymorphisms influence the development of skin rash arising from treatment with EGF receptor inhibitors.

Pharmacogenomics - 1 Oct 2012

Fuerst Daniel, Parmar Sumit, Schumann Christian, Rüdiger Stefan, Boeck Stefan, Heinemann Volker, Kaechele Volker, Stiebel Kristina, Paul Tanusree, Seufferlein Thomas, Mytilineos Joannis, Stingl Julia Carolin

Abstract excerpt

AIM: Development of a skin rash under treatment with EGF receptor (EGFR) inhibitors (EGFRIs) has been linked to a favorable prognosis in some studies, suggesting a possible immunological role for EGFRIs in addition to direct antagonistic downstream effects. The present study aimed to investigate whether particular HLA polymorphisms found in cancer patients treated with EGFRIs are associated with the development...

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Identifiers

PMID: 23057547
DOI: 10.2217/pgs.12.122

Genes

EGF
EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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