A toll-like receptor 3 single nucleotide polymorphism in Japanese patients with sarcoidosis.

doi:10.1111/tan.12535

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A toll-like receptor 3 single nucleotide polymorphism in Japanese patients with sarcoidosis.

Tissue antigens - 1 Mar 2015

Ikezoe K, Handa T, Tanizawa K, Kubo T, Ito I, Sokai A, Nakatsuka Y, Nagai S, Izumi T, Mishima M

Abstract excerpt

Toll-like receptor 3 (TLR3) may be associated with T helper 1 immune response. This study aimed to investigate the role of a functional TLR3 single nucleotide polymorphism (SNP) in sarcoidosis. We genotyped 220 Japanese patients with sarcoidosis and 140 controls for TLR3 SNP rs3775291 to analyze its association with susceptibility to sarcoidosis and assessed its relationship to clinical features in 172 patients...

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PMID: 25720507
DOI: 10.1111/tan.12535

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TLR3

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