Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA hypermethylation analysis in sputum for the diagnosis of lung cancer: training validation set approach

26 Feb 2015

Abstract excerpt

BACKGROUND: Lung cancer has the highest mortality of all cancers. The aim of this study was to examine DNA hypermethylation in sputum and validate its diagnostic accuracy for lung cancer. METHODS: DNA hypermethylation of RASSF1A, APC, cytoglobin, 3OST2, PRDM14, FAM19A4 and PHACTR3 was analysed in sputum samples from symptomatic lung cancer patients and controls (learning set: 73 cases, 86 controls; validation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Research and Disease Studies
Share to Epigenetics and DNA Methylation
Share to Lung Cancer Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25719833
DOI: 10.1038/bjc.2014.636

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA hypermethylation analysis in sputum for the diagnosis of lung cancer: training validation set approachPMID 25719833Read ↗

Identification of a panel of sensitive and specific DNA methylation markers for lung adenocarcinomaSemantic proximity Read ↗

Defining a gene promoter methylation signature in sputum for lung cancer risk assessment.Semantic proximity Read ↗

Gene Promoter Methylation in Plasma and Sputum Increases with Lung Cancer RiskSemantic proximity Read ↗

Subtyping Lung Cancer Using DNA Methylation in Liquid BiopsiesSemantic proximity Read ↗

Early Detection of Lung Cancer Using DNA Promoter Hypermethylation in Plasma and SputumSemantic proximity Read ↗

A Panel of DNA Methylation Biomarkers for Detection and Improving Diagnostic Efficiency of Lung CancerSemantic proximity Read ↗

Precision Oncology: Artificial Intelligence and DNA Methylation Analysis of Circulating Cell-Free DNA for Lung Cancer DetectionSemantic proximity Read ↗

Genome-wide analysis of DNA methylation in bronchial washingsSemantic proximity Read ↗

Identification of novel epigenetic abnormalities as sputum biomarkers for lung cancer risk among smokers and COPD patientsSemantic proximity Read ↗

Molecular Alterations in Spontaneous Sputum of Cancer-Free Heavy Smokers: Results from a Large Screening ProgramSemantic proximity Read ↗

Quantitative assessment of lung cancer associated with genes methylation in the peripheral blood.Semantic proximity Read ↗

Methylation of L1RE1, RARB, and RASSF1 function as possible biomarkers for the differential diagnosis of lung cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.