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Article

Subtyping Lung Cancer Using DNA Methylation in Liquid Biopsies

19 Sept 2019

Abstract excerpt

Background: Lung cancer (LCa) is the most frequently diagnosed and lethal cancer worldwide. Histopathological subtyping, which has important therapeutic and prognostic implications, requires material collection through invasive procedures, which might be insufficient to enable definitive diagnosis. Aberrant DNA methylation is an early event in carcinogenesis, detectable in circulating cell-free DNA (ccfDNA)....

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PMID: 31546933
DOI: 10.3390/jcm8091500

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