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Article

SIRT2 suppresses non-small cell lung cancer growth by targeting JMJD2A

21 Feb 2015

Abstract excerpt

Lung cancer has been the most prolific cancer in China - as in the rest of the world - with a high death rate and low 5-year survival rate. Previous evidence showed that JMJD2A is over-expressed in human non-small cell lung cancer (NSCLC) tissues compared to adjacent normal tissues, and that high level of JMJD2A predicts poor overall and disease-free survival. However, the mechanism by which JMJD2A is regulated...

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PMID: 25719312
DOI: 10.1515/hsz-2014-0284

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