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Article

Golgi anti-apoptotic proteins are highly conserved ion channels that affect apoptosis and cell migration.

The Journal of biological chemistry - 1 May 2015

Carrara Guia, Saraiva Nuno, Parsons Maddy, Byrne Bernadette, Prole David L, Taylor Colin W, Smith Geoffrey L

Abstract excerpt

Golgi anti-apoptotic proteins (GAAPs) are multitransmembrane proteins that are expressed in the Golgi apparatus and are able to homo-oligomerize. They are highly conserved throughout eukaryotes and are present in some prokaryotes and orthopoxviruses. Within eukaryotes, GAAPs regulate the Ca(2+) content of intracellular stores, inhibit apoptosis, and promote cell adhesion and migration. Data presented here...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 25713081
DOI: 10.1074/jbc.M115.637306
PMCID: PMC4416878

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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