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The anti-apoptotic Coxiella burnetii effector protein AnkG is a strain specific virulence factor

21 Sept 2020

Abstract excerpt

The ability to inhibit host cell apoptosis is important for the intracellular replication of the obligate intracellular pathogen Coxiella burnetii, as it allows the completion of the lengthy bacterial replication cycle. Effector proteins injected into the host cell by the C. burnetii type IVB secretion system (T4BSS) are required for the inhibition of host cell apoptosis. AnkG is one of these anti-apoptotic...

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PMID: 32958854
DOI: 10.1038/s41598-020-72340-9

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