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Article

Mutagenic potential of the isoflavone irilone in cultured V79 cells.

Toxicology letters - 16 Apr 2015

Scheffler Anne, Albrecht Annette E, Esch Harald L, Lehmann Leane

Abstract excerpt

After consumption of red clover-based dietary supplements, plasma concentrations of the isoflavone irilone (IRI) equal that of the well-investigated daidzein. Since some isoflavones are genotoxic, the potential of IRI to induce mutations was investigated. Gene mutations were determined by hypoxanthine-guanine phosphoribosyltransferase (HPRT) assay and sequencing of mutant cDNA, chromosome and genome mutations by...

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Identifiers

PMID: 25703823
DOI: 10.1016/j.toxlet.2015.02.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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