Article
Imprinted genes in myeloid lineage commitment in normal and malignant hematopoiesis.
Leukemia - 1 Jun 2015
Benetatos L, Vartholomatos G
Abstract excerpt
Genomic imprinting is characterized by the parent-of-origin monoallelic expression of several diploid genes because of epigenetic regulation. Imprinted genes (IGs) are key factors in development, supporting the ability of a genotype to produce phenotypes in response to environmental stimuli. IGs are highly expressed during prenatal stages but are downregulated after birth. They also affect aspects of life other...
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