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Epigenetics and imprinting in human disease

1 Jan 2014

Abstract excerpt

Most genes are expressed from both parental chromosomes; however, a small number of genes in mammals are imprinted and expressed in a parent-of-origin specific manner. These imprinted genes play an important role in embryonic and extraembryonic growth and development, as well as in a variety of processes after birth. Many imprinted genes are clustered in the genome with the establishment and maintenance of...

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PMID: 25023695
DOI: 10.1387/ijdb.140077mb

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