Article
Role of DNA methylation in imprinting disorders: an updated review.
Journal of assisted reproduction and genetics - 1 May 2017
Elhamamsy Amr Rafat
Abstract excerpt
Genomic imprinting is a complex epigenetic process that contributes substantially to embryogenesis, reproduction, and gametogenesis. Only small fraction of genes within the whole genome undergoes imprinting. Imprinted genes are expressed in a monoallelic parent-of-origin-specific manner, which means that only one of the two inherited alleles is expressed either from the paternal or maternal side. Imprinted genes...
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