Article
Genomic imprinting relevant to genetic diseases.
The Southeast Asian journal of tropical medicine and public health - 1 Jan 1997
Niikawa N
Abstract excerpt
Genomic imprinting is a new concept proposed to explain unusual observations in early mammalian development, the occurrence of certain genetic diseases, genetic anticipation or incomplete penetrance, and tumorigenesis. The basic mechanism of the imprinting has remained obscure, although DNA-methy...
Topics
- Angelman Syndrome
- Animals
- Beckwith-Wiedemann Syndrome
- Chromatin
- DNA Methylation
- Genetic Diseases, Inborn
- Genomic Imprinting
- Humans
- Kidney Neoplasms
- Mice
- Phenotype
- Prader-Willi Syndrome
- Wilms Tumor