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Article

Modulation of PPARγ Provides New Insights in a Stress Induced Premature Senescence Model

7 Aug 2014

Abstract excerpt

Peroxisome proliferator-activated receptor gamma (PPARγ) may be involved in a key mechanism of the skin aging process, influencing several aspects related to the age-related degeneration of skin cells, including antioxidant unbalance. Therefore, we investigated whether the up-modulation of this nuclear receptor exerts a protective effect in a stress-induced premature senescence (SIPS) model based on a single...

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PMID: 25101957
DOI: 10.1371/journal.pone.0104045

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