Article

Deep2Full: Predictive model for complementing phenotypic outcomes in a deep mutational scan using protein sequence and structure information

2017-11-10

Abstract excerpt

Large scale mutagenesis experiments are becoming possible owing to the advancement in the sequencing technologies and high throughput screening. Deep mutational scans perform exhaustive single-point muta-tions on a protein and probe their phenotypic effects. Performing a full scan with site-directed mutations of all the amino acid residues in a protein may not be practical, and may not even be required, especially...

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Literature Corpus work: 1f560556-4120-54bf-bbd8-728ae6235b5b
DOI: 10.1101/217158

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