Article
Functional census of mutation sequence spaces: the example of p53 cancer rescue mutants.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Danziger Samuel A, Swamidass S Joshua, Zeng Jue, Dearth Lawrence R, Lu Qiang, Chen Jonathan H, Cheng Jianlin, Hoang Vinh P, Saigo Hiroto, Luo Ray, Baldi Pierre, Brachmann Rainer K, Lathrop Richard H
Abstract excerpt
Many biomedical problems relate to mutant functional properties across a sequence space of interest, e.g., flu, cancer, and HIV. Detailed knowledge of mutant properties and function improves medical treatment and prevention. A functional census of p53 cancer rescue mutants would aid the search fo...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.