Article
Infection with the carcinogenic liver fluke <i>Opisthorchis viverrini</i> modifies intestinal and biliary microbiome
7 Aug 2013
Abstract excerpt
Opisthorchis viverrini is a fish-borne trematode endemic in East Asia. Following ingestion, the flukes locate to the biliary tre where chronic infection frequently leads to cholangiocarcinoma (CCA). The mechanisms by which O. viverrini infection culminates in CCA remain unknown. An unexplored aspect is its influence on the host microbiome. In the hamster, infection with this pathogen reliably leads to CCA....
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