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Article

Synergistic effects of ATP and RNA binding to human DEAD-box protein DDX1.

Nucleic acids research - 11 Mar 2015

Kellner Julian N, Reinstein Jochen, Meinhart Anton

Abstract excerpt

RNA helicases of the DEAD-box protein family form the largest group of helicases. The human DEAD-box protein 1 (DDX1) plays an important role in tRNA and mRNA processing, is involved in tumor progression and is also hijacked by several virus families such as HIV-1 for replication and nuclear export. Although important in many cellular processes, the mechanism of DDX1's enzymatic function is unknown. We have...

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Share to Adenosine Diphosphate
Share to Adenosine Triphosphatases
Share to Adenosine Triphosphate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Binding, Competitive

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Source

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Identifiers

PMID: 25690890
DOI: 10.1093/nar/gkv106
PMCID: PMC4357711

Genes

DDX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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