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Article

Use of mutation specific antibodies to detect EGFR status in small biopsy and cytology specimens of lung adenocarcinoma.

Lung cancer (Amsterdam, Netherlands) - 1 Aug 2012

Hasanovic Adnan, Ang Daphne, Moreira Andre L, Zakowski Maureen F

Abstract excerpt

BACKGROUND: EGFR mutation status is the best predictor of response to tyrosine kinase inhibitors (TKIS) in primary lung adenocarcinoma. Approximately 70% of lung cancers are diagnosed in advanced stages where small biopsies and cytological specimens are the only source of material for both diagnosis and mutation testing. Specific antibodies that can detect mutant EGFR protein were evaluated for the detection of...

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Source

Identifiers

PMID: 22542171
DOI: 10.1016/j.lungcan.2012.04.004

Genes

EGFR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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