Article
Epidermal growth factor receptor mutation-specific immunohistochemical antibodies in lung adenocarcinoma.
Histopathology - 1 May 2014
Allo Ghassan, Bandarchi Bizhan, Yanagawa Naoki, Wang Ami, Shih Warren, Xu Jing, Dalby Morgan, Nitta Hiroaki, To Christine, Liu Ni, Sykes Jenna, Tsao Ming S
Abstract excerpt
AIMS: We investigated the sensitivity and specificity of two novel Epidermal growth factor receptor (EGFR) mutation-specific antibodies in the detection of the most common EGFR mutations in lung adenocarcinoma. METHODS AND RESULTS: A total of 241 resected lung adenocarcinoma specimens and six resected post-neoadjuvant gefitinib adenocarcinomas were analysed for EGFR mutation using mass spectrometry, fragment...
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