Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Diamond: immunohistochemistry versus sequencing in EGFR analysis of lung adenocarcinomas.

Journal of clinical pathology - 1 May 2016

Ragazzi Moira, Tamagnini Ione, Bisagni Alessandra, Cavazza Alberto, Pagano Maria, Baldi Licia, Boni Corrado, Cantile Flavia, Barbieri Fausto, Nicoli Davide, Sartori Giuliana, de Biase Dario, Gardini Giorgio, Rossi Giulio

Abstract excerpt

AIMS: Identification of epidermal growth factor receptor (EGFR) mutations in lung adenocarcinomas is the single most important predictor of clinical response and outcome using EGFR tyrosine kinase inhibitors (TKIs). EGFR E746-A750del and L858R mutations are the most common gene alterations, also predicting the best clinical response to TKIs. We evaluated the accuracy of EGFR mutation-specific antibodies in a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ErbB Receptors

Share to High-Throughput Nucleotide Sequencing

Share to Immunohistochemistry

Share to Lung Neoplasms

Share to Sensitivity and Specificity

Source

Identifiers

PMID: 26553934
DOI: 10.1136/jclinpath-2015-203348

Genes

EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Diamond: immunohistochemistry versus sequencing in EGFR analysis of lung adenocarcinomas.PMID 26553934Read ↗

EGFR mutation-specific antibodies in pulmonary adenocarcinoma: a comparison with DNA direct sequencing.Semantic proximity Read ↗

Identification of EGFR Mutations by Immunohistochemistry with EGFR Mutation-Specific Antibodies in Biopsy and Resection Specimens from Pulmonary Adenocarcinoma.Semantic proximity Read ↗

EGFR Status Assessment for Better Care of Early Stage Non-Small Cell Lung Carcinoma: What Is Changing in the Daily Practice of Pathologists?Semantic proximity Read ↗

Epidermal growth factor receptor mutation-specific immunohistochemical antibodies in lung adenocarcinoma.Semantic proximity Read ↗

Molecular diagnostics of lung carcinomas.Semantic proximity Read ↗

Diagnostic value of mutation-specific antibodies for immunohistochemical detection of epidermal growth factor receptor mutations in non-small cell lung cancer: a meta-analysis.Semantic proximity Read ↗

Immunohistochemical detection of mutations in the epidermal growth factor receptor gene in lung adenocarcinomas using mutation-specific antibodies.Semantic proximity Read ↗

Immunohistochemistry to identify EGFR mutations or ALK rearrangements in patients with lung adenocarcinoma.Semantic proximity Read ↗

Does Immunohistochemistry Represent a Robust Alternative Technique in Determining Drugable Predictive Gene Alterations in Non-Small Cell Lung Cancer?Semantic proximity Read ↗

Assessment of EGFR mutation status in lung adenocarcinoma by immunohistochemistry using antibodies specific to the two major forms of mutant EGFR.Semantic proximity Read ↗

[Immunohistochemistry and personalised medicine in lung oncology: advantages and limitations].Semantic proximity Read ↗

EGFR analysis: current evidence and future directions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.