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Article

EGFR mutation-specific antibodies in pulmonary adenocarcinoma: a comparison with DNA direct sequencing.

Applied immunohistochemistry & molecular morphology : AIMM - 1 Jul 2012

Ambrosini-Spaltro Andrea, Campanini Nicoletta, Bortesi Beatrice, Azzoni Cinzia, Naldi Nadia, Ampollini Luca, Tiseo Marcello, Ardizzoni Andrea, Rusca Michele, Carbognani Paolo, Silini Enrico M

Abstract excerpt

INTRODUCTION: Epidermal growth factor receptor (EGFR) gene mutations are usually detected by direct sequencing to identify patients with advanced pulmonary adenocarcinomas as candidates for tyrosine kinase inhibitor therapy. The aim of the study was to evaluate the efficacy of EGFR mutation-specific antibodies in identifying EGFR-mutated adenocarcinomas. MATERIALS AND METHODS: Thirty-three consecutive cases of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22710815
DOI: 10.1097/PAI.0b013e31823e064b

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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