Impact of tissue type and content of neoplastic cells of samples on the quality of epidermal growth factor receptor mutation analysis among patients with lung adenocarcinoma.

doi:10.3892/mmr.2015.3347

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Article

Impact of tissue type and content of neoplastic cells of samples on the quality of epidermal growth factor receptor mutation analysis among patients with lung adenocarcinoma.

Molecular medicine reports - 1 Jul 2015

Paliogiannis Panagiotis, Attene Federico, Cossu Antonio, Defraia Efisio, Porcu Giuseppe, Carta Annamaria, Sotgiu Maria Ignazia, Pazzola Antonio, Cordero Lorenzo, Capelli Francesca, Fadda Giovanni Maria, Ortu Salvatore, Sotgiu Giovanni, Palomba Grazia, Sini Maria Cristina, Palmieri Giuseppe, Colombino Maria

Abstract excerpt

Assessment of the epidermal growth factor receptor (EGFR) mutational status has become crucial in recent years in the molecular classification of patients with lung cancer. The impact of the type and quantity of malignant cells of the neoplastic specimen on the quality of mutation analysis remains to be elucidated, and only empirical and sporadic data are available. The aim of the present study was to investigate...

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PMID: 25683726
DOI: 10.3892/mmr.2015.3347
PMCID: PMC4438954

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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