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Article

Detection of EGFR gene mutations in non-small cell lung cancer: lessons from a single-institution routine analysis of 1,403 tumor samples.

International journal of oncology - 1 Oct 2013

Vallee Audrey, Sagan Christine, Le Loupp Anne-Gaelle, Bach Kalyane, Dejoie Thomas, Denis Marc G

Abstract excerpt

Activating mutations of the epidermal growth factor receptor (EGFR) in lung tumors are associated with a dramatic response to tyrosine kinase inhibitors. Therefore, routine analysis of pathological specimens is mandatory in clinical practice. We have prospectively tested tumors from Caucasian lung tumor patients between January 2010 and June 2012. DNA was extracted from formalin-fixed paraffin-embedded tissues...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23934203
DOI: 10.3892/ijo.2013.2056
PMCID: PMC3829780

Genes

EGFR

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