Determining Risk of Colorectal Cancer and Starting Age of Screening Based on Lifestyle, Environmental, and Genetic Factors.

doi:10.1053/j.gastro.2018.02.021

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Determining Risk of Colorectal Cancer and Starting Age of Screening Based on Lifestyle, Environmental, and Genetic Factors.

Gastroenterology - 1 Jun 2018

Jeon Jihyoun, Du Mengmeng, Schoen Robert E, Hoffmeister Michael, Newcomb Polly A, Berndt Sonja I, Caan Bette, Campbell Peter T, Chan Andrew T, Chang-Claude Jenny, Giles Graham G, Gong Jian, Harrison Tabitha A, Huyghe Jeroen R, Jacobs Eric J, Li Li, Lin Yi, Le Marchand Loïc, Potter John D, Qu Conghui, Bien Stephanie A, Zubair Niha, Macinnis Robert J, Buchanan Daniel D, Hopper John L, Cao Yin, Nishihara Reiko, Rennert Gad, Slattery Martha L, Thomas Duncan C, Woods Michael O, Prentice Ross L, Gruber Stephen B, Zheng Yingye, Brenner Hermann, Hayes Richard B, White Emily, Peters Ulrike, Hsu Li

Abstract excerpt

BACKGROUND & AIMS: Guidelines for initiating colorectal cancer (CRC) screening are based on family history but do not consider lifestyle, environmental, or genetic risk factors. We developed models to determine risk of CRC, based on lifestyle and environmental factors and genetic variants, and to identify an optimal age to begin screening. METHODS: We collected data from 9748 CRC cases and 10,590 controls in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Colonoscopy

Share to Early Detection of Cancer

Share to Environment

Share to Life Style

Share to Practice Guidelines as Topic

Share to ROC Curve

Share to Sex Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 29458155
DOI: 10.1053/j.gastro.2018.02.021
PMCID: PMC5985207

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Determining Risk of Colorectal Cancer and Starting Age of Screening Based on Lifestyle, Environmental, and Genetic Factors.PMID 29458155Read ↗

A model to determine colorectal cancer risk using common genetic susceptibility loci.Semantic proximity Read ↗

Risk Stratification for Early-Onset Colorectal Cancer Using a Combination of Genetic and Environmental Risk Scores: An International Multi-Center Study.Semantic proximity Read ↗

A new colorectal cancer risk prediction model incorporating family history, personal and environmental factorsSemantic proximity Read ↗

Early-onset colorectal cancer: A review of current knowledgeSemantic proximity Read ↗

Genetic prediction of colorectal cancer risk in six major ancestries provides insights to streamline practice screening guidelinesSemantic proximity Read ↗

A New Comprehensive Colorectal Cancer Risk Prediction Model Incorporating Family History, Personal Characteristics, and Environmental Factors.Semantic proximity Read ↗

Decoding the genetic and environmental forces in propelling the surge of early-onset colorectal cancerSemantic proximity Read ↗

Early-onset Colorectal Cancer is Distinct From Traditional Colorectal Cancer.Semantic proximity Read ↗

Family history and age at initiation of colorectal cancer screening.Semantic proximity Read ↗

Ability of known susceptibility SNPs to predict colorectal cancer risk for persons with and without a family historySemantic proximity Read ↗

Cumulative Burden of Colorectal Cancer-Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer.Semantic proximity Read ↗

Estimation of Absolute Risk of Colorectal Cancer Based on Healthy Lifestyle, Genetic Risk, and Colonoscopy Status in a Population-Based Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.