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Article

GWAS-identified loci for coronary heart disease are associated with intima-media thickness and plaque presence at the carotid artery bulb.

Atherosclerosis - 1 Apr 2015

den Hoed Marcel, Strawbridge Rona J, Almgren Peter, Gustafsson Stefan, Axelsson Tomas, Engström Gunnar, de Faire Ulf, Hedblad Bo, Humphries Steve E, Lindgren Cecilia M, Morris Andrew P, Östling Gerd, Syvänen Ann-Christine, Tremoli Elena, Hamsten Anders, Ingelsson Erik, Melander Olle, Lind Lars

Abstract excerpt

BACKGROUND: Large-scale genome-wide association studies (GWAS) have so far identified 45 loci that are robustly associated with coronary heart disease (CHD) in data from adult men and women of European descent. OBJECTIVES: To examine whether the CHD-associated loci are associated with measures of atherosclerosis in data from up to 9582 individuals of European ancestry. METHODS: Forty-five SNPs representing the...

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Share to Carotid Artery, Common
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25682028
DOI: 10.1016/j.atherosclerosis.2015.01.032
PMCID: PMC5526440

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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