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Article

Human EP2 prostanoid receptors exhibit more constraints to mutations than human DP prostanoid receptors.

FEBS letters - 12 Mar 2015

Tanimoto Jun, Fujino Hiromichi, Takahashi Hiroki, Murayama Toshihiko

Abstract excerpt

Human D-type prostanoid (DP) and E-type prostanoid 2 (EP2) receptors are regarded as the most closely related receptors among prostanoid receptors. Although these receptors are generated by tandem duplication, their physiological outputs often oppose one another. In the present study, we extracted mutations occurring in the coding regions of both receptors using the 1000 genome project database and found that EP2...

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PMID: 25681680
DOI: 10.1016/j.febslet.2015.02.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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