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Article

A Candidate Gene Association Study Identifies DAPL1 as a Female-Specific Susceptibility Locus for Age-Related Macular Degeneration (AMD).

Neuromolecular medicine - 1 Jun 2015

Grassmann Felix, Friedrich Ulrike, Fauser Sascha, Schick Tina, Milenkovic Andrea, Schulz Heidi L, von Strachwitz Claudia N, Bettecken Thomas, Lichtner Peter, Meitinger Thomas, Arend Nicole, Wolf Armin, Haritoglou Christos, Rudolph Guenther, Chakravarthy Usha, Silvestri Giuliana, McKay Gareth J, Freitag-Wolf Sandra, Krawczak Michael, Smith R Theodore, Merriam John C, Merriam Joanna E, Allikmets Rando, Heid Iris M, Weber Bernhard H F

Abstract excerpt

Age-related macular degeneration (AMD) is the leading cause of blindness among white caucasians over the age of 50 years with a prevalence rate expected to increase markedly with an anticipated increase in the life span of the world population. To further expand our knowledge of the genetic archi...

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Source

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Identifiers

PMID: 25680934
DOI: 10.1007/s12017-015-8342-1
PMCID: PMC4419162

Genes

DAPL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25680934-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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A Candidate Gene Association Study Identifies DAPL1 as a Female-Specific Susceptibility Locus for Age-Related Macular Degeneration (AMD).PMID 25680934Read ↗

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DAPL1, a susceptibility locus for age-related macular degeneration, acts as a novel suppressor of cell proliferation in the retinal pigment epitheliumSemantic proximity Read ↗

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