Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rare variants and loci for age-related macular degeneration in the Ohio and Indiana Amish.

Human genetics - 1 Oct 2019

Waksmunski Andrea R, Igo Robert P, Song Yeunjoo E, Cooke Bailey Jessica N, Laux Renee, Fuzzell Denise, Fuzzell Sarada, Adams Larry D, Caywood Laura, Prough Michael, Stambolian Dwight, Scott William K, Pericak-Vance Margaret A, Haines Jonathan L

Abstract excerpt

Age-related macular degeneration (AMD) is a leading cause of blindness in the world. While dozens of independent genomic variants are associated with AMD, about one-third of AMD heritability is still unexplained. To identify novel variants and loci for AMD, we analyzed Illumina HumanExome chip data from 87 Amish individuals with early or late AMD, 79 unaffected Amish individuals, and 15 related Amish individuals...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computational Biology
Share to Gene Ontology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Genetic Linkage

Share to Macular Degeneration

Share to Pedigree

Share to Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 31367973
DOI: 10.1007/s00439-019-02050-4
PMCID: PMC6745026

Genes

CGRRF1
DLGAP1
LCN9
RTEL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rare variants and loci for age-related macular degeneration in the Ohio and Indiana Amish.PMID 31367973Read ↗

Rare complement factor H variant associated with age-related macular degeneration in the Amish.Semantic proximity Read ↗

Highly penetrant alleles in age-related macular degeneration.Semantic proximity Read ↗

Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced diseaseSemantic proximity Read ↗

Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease.Semantic proximity Read ↗

Seven new loci associated with age-related macular degeneration.Semantic proximity Read ↗

Whole Genome Sequencing Identifies Novel Common and Low-Frequency Variants Associated With Age-Related Macular Degeneration.Semantic proximity Read ↗

Whole exome sequencing of extreme age-related macular degeneration phenotypes.Semantic proximity Read ↗

Whole genome sequencing of 4,787 individuals identifies gene-based rare variants in age-related macular degeneration.Semantic proximity Read ↗

New loci and coding variants confer risk for age-related macular degeneration in East Asians.Semantic proximity Read ↗

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.Semantic proximity Read ↗

Genetic mechanisms and age-related macular degeneration: common variants, rare variants, copy number variations, epigenetics, and mitochondrial genetics.Semantic proximity Read ↗

Identification of Genetic Variants for Risk Prediction and Early Diagnosis of Age-Related Macular Degeneration in the Taiwanese Population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.