Article
Significant association between IL23R and IL17F polymorphisms and clinical features of colorectal cancer.
Immunology letters - 1 Jan 2000
Omrane Inés, Baroudi Olfa, Bougatef Karim, Mezlini Amel, Abidi Ahmed, Medimegh Imen, Stambouli Nejla, Ayari Hager, Kourda Nadia, Uhrhammer Nancy, Bignon Yves Jean, Benammar Elgaaied Amel, Marrakchi Raja
Abstract excerpt
Th17cells are involved in inflammatory and autoimmune diseases. These cells may be involved in pathological processes mainly producing pro-inflammatory cytokines. Recently, it was shown that the IL23/IL17 pathway plays an important role in the development of inflammatory bowel disease. In general...
Topics
- Aged
- Carcinogenesis
- Carcinoma
- Colorectal Neoplasms
- DNA Mutational Analysis
- Female
- Genetic Association Studies
- Genetic Predisposition to Disease
- Humans
- Inflammation Mediators
- Interleukin-17
- Male
- Middle Aged
- Neoplasm Metastasis