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Association Study Between DRD2, DRD3 Genetic Polymorphisms and Adverse Reactions in Chinese Patients on Amisulpride Treatment.

Pharmacopsychiatry - 1 Nov 2024

Qu Kankan, He Yanan, Zhang Zhongdong, Cao Yeli, Qin Qiyun, Zhou Zhenhe, Zhen Lili

Abstract excerpt

OBJECTIVE: To determine if the cardiac function and "endocrinium" of Chinese patients are associated with dopamine D2 (DRD2) (rs6276) and DRD3 (rs6280, rs963468) genetic polymorphisms when treated with amisulpride. METHODS: This study enrolled 148 patients with schizophrenia who took amisulpride orally for 8 weeks. DRD2 (rs6276) and DRD3 (rs6280, ) genetic polymorphisms were detected with TaqMan-MGB...

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PMID: 39187246
DOI: 10.1055/a-2375-3859

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