Article
Monoamine oxidase: radiotracer chemistry and human studies.
Journal of labelled compounds & radiopharmaceuticals - 1 Mar 2015
Fowler Joanna S, Logan Jean, Shumay Elena, Alia-Klein Nelly, Wang Gene-Jack, Volkow Nora D
Abstract excerpt
Monoamine oxidase (MAO) oxidizes amines from both endogenous and exogenous sources thereby regulating the concentration of neurotransmitter amines such as serotonin, norepinephrine, and dopamine as well as many xenobiotics. MAO inhibitor drugs are used in the treatment of Parkinson's disease and in depression stimulating the development of radiotracer tools to probe the role of MAO in normal human biology and in...
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